The Science – Vitamins & Supplements
Green Tea (EGCG)
A powerful nutrient backed by numerous studies that show the potential antitumor benefit of Epigallocatechin Gallate (EGCG) on prostate cancer. Positive activity observed as a single agent or with synergistic effects when used with other nutrients. Manufacturers of green tea supplements characterize their products in many different ways (catechins, polyphenols, EGCG, etc.) and it’s vital to select the right product based on the specified EGCG level.
Studies have shown that quercetin, a natural flavonoid, works synergistically with Green Tea (EGCG) to dramatically increase (double) the inhibition of tumor growth of prostate cancer cells as compared to using EGCG alone.
An interesting nutrient composed of a standardized extract of rye pollen (Secale cereale), corn pollen (Zea mays) and timothy pollen (Phleum pratense) that supports overall prostate health. The extract contains a blend of water-soluble and lipid-soluble fractions that have exhibited anti-inflammatory properties through the inhibition of the prostaglandin and leukotrien synthesis. Regularly used in Europe to provide symptomatic relief for men experiencing urinary tract disorders including benign prostate hyperplasia (BPH), prostatodynia, acute and chronic prostatitis caused by a bacterial infection and acute and chronic abacterial prostatitis.
Studies have shown the potential of pomegranate to significantly reduce the rate at which the PSA levels rose in men who were diagnosed with prostate cancer.
This interesting compound has demonstrated significant effects on cell proliferation, apoptosis and androgen receptor (AR) expression in studies that applied it to human prostate cancer cells. We recommend a novel way to take this supplement to boost its rapid adsorption into the body and enhance its bioavailability to potentially produce beneficial effects.
A special fraction (active hexose-correlated compound ) derived from different mushrooms has been shown to stimulate the immune system to fight many different types of cancers, including prostate cancer.
The highly publicized Cancer Prevention Trial (SELECT) human trial concluded that vitamin E (α-tocopheryl acetate) and selenium (L-selenomethionine) were not effective in combination against prostate cancer. But, a special form of Vitamin E (gamma fraction) has been shown to have an effect when used in a study where the compound was applied to human prostate tumors implanted in mice. We continue to recommend taking Vitamin E, but only this special form.
Vitamin D is synthesized in the human skin from sunlight and through dietary intake. A human study demonstrated that taking Vitamin D-3 increases the level of calcitriol in prostate tissues and can produce moderate benefits in lowering PSA and the parathyroid hormone (PTH).
A little known supplement in the flavonoid family that has been shown to exhibit anticancer effects on several cancers, including prostate cancer. The uptake of apigenin into prostate cells (both normal and cancerous cells) seems to be an important characteristic that facilitates its positive action.
Many studies have shown a correlation between increased intake of lycopene (ex: from tomatoes) and decreased risk of prostate cancer. We recommend taking lycopene that is derived only from natural sources because
synthetic forms typically don’t include other potentially synergistic compounds.
Diets rich in broccoli have been associated with a reduction in risk of prostate cancer progression. Sulforaphane is believed to be the compound that is responsible for this correlation. An initial human trial suggest the potential for a positive effect, but additional studies using higher dosage levels of sulforaphane need to be explored.
Broad Spectrum Nutrients (Zinc, etc.)
We believe in using a broad array of other nutrients that support general prostate health.